Laser-Induced Fluorescence for Imaging Cancer Cells

Abstract

Cancer is one of the deadly diseases that threaten human life, so many researchers have studied diagnostic techniques as a step before surgery. These techniques are considered one of the effective methods in early detection of cancer cells. One of these modern methods is the use of laser fluorescence spectrum to image tumors, as this method has several advantages, including high sensitivity and locating the tumor in the body. In this research, the possibility of a laser operating in the visual region (532 nm) and silver nanoparticles is studied for vivo imaging of various cancerous tumors. The used detector, CCD (Genetic) type, with high sensitivity, in addition to an optical analyzer of the ocean 2000 type. A type of optical microscope was used to study the surface behavior of the tissue. The ability to diagnose the affected area using the laser induced fluorescence spectrum was observed at a very high rate, in addition to changes in the intensity of the fluorescence spectra, and the use of nanoparticles helped to identify affected cells within a single tissue.